Baseline editing shows potential superiority for treating sickle cell disease

St. Jude Hematology

image: (Left to right) Co-corresponding author Mitchell Weiss, MD, Ph.D., St. Jude Department of Hematology chair and co-corresponding author Jonathan Yen, Ph.D., St. Jude Therapeutic Genome engineering director at a microscope in the laboratory. visualization Moreover Credit: St. Jude Children’s Research Hospital Gene therapy that alters hemoglobin genes may be a response to treatment for … Read more

The Neanderthal handshake: unraveling the genetic origins of Viking disease

Vikings disease folded hand

A ring finger stuck in a bent position as seen in Dupuytrens disease, colloquially known as Viking disease. Credit: Hugo Zeberg/Molecular Biology and Evolution Dupuytrens disease, a hand disorder common among Northern Europeans, has genetic ties to Neanderthals, according to a study in Molecular Biology and Evolution. Three of the 61 genetic risk variants for … Read more